Research Studies

How do I learn more about current open studies?

Below you will find a list of current studies. Clicking on the link will take you to the study summary, which will provide you with all the important details for each study.

How do I participate in a study?

Each study summary provides a list of hospitals or clinics where the study is being run. Using the contact information provided, you may contact any of these facilities in order to request participation in a study.

Showing All Ongoing CEGIR Studies

Recruiting

7801: A Prospective, Multicenter Study to Compare and Validate Endoscopic, Histologic, Molecular, and Patient-Reported Outcomes in Pediatric and Adult Patients with Eosinophilic Esophagitis (EoE), Gastritis (EoG), Colitis (EoC) and Enteritis (EoN)

CEGIR is conducting this study because they want to learn more about Eosinophilic Gastrointestinal Diseases (EGIDs). As part of that goal, one area of study will compare how well a patient feels – their symptoms – with what the tissue samples look like under a microscope. The study aims to answer a series of questions, including the following: - What if the tissue looks good, but you are still experiencing symptoms? - What if the symptoms have subsided, but the eosinophil counts haven’t changed?

7811: An Open-Label Study Of Zemaira (Alpha 1-Trypsin Inhibitor) In Subjects With Eosinophilic Esophagitis

This is a phase 2, open-label trial testing the efficacy and safety of Zemaira in EoE. Qualifying participants will receive weekly intravenous infusions of 120 mg/kg body weight (BW) dose/week for 8 weeks for a total of 8 infusions. All participants will be followed for an additional 12 weeks after the last dose of study drug.

7812: Pilot Assessment to Find Evidence of Gastric Motility Abnormalities in Eosinophilic Gastric Disorders (OAT-FEED)

The study is a cross-sectional observational study designed to determine if eosinophilic gastritis (EoG) results in gastric mobility impairment.

Closed to Recruiting

7801-sub-study: Role of the Intestinal Microbiome in Eosinophilic Esophagitis (EoE), Eosinophilic Gastritis (EoG), and Eosinophilic Colitis (EoC)

7802: Six Food vs One Food Eosinophilic Esophagitis Elimination Diet followed by Swallowed Glucocorticoid Trial - SOFEED

7803: A Preliminary Open-Label Trial of Losartan Potassium in Participants with Eosinophilic Esophagitis (EoE) With or Without a Connective Tissue Disorder

7806: Demographics, Clinical Characteristics, and Pathology of Eosinophilic Gastritis, Enteritis, and Colitis in a Multi-Site Cohort

7807: Validation of Online Cohort of Eosinophilic Gastrointestinal Disorder (EGID) Patients Enrolled in RDCRN CEGIR Contact Registry

7808: Use of Unsedated Transnasal Esophagoscopy to Monitor Dietary Management of Eosinophilic Esophagitis in Children

7809: Effect of Elemental Diet on Adult Patients with Eosinophilic Enteritis (ELEMENT)

7810: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Evaluate the Efficacy of Dupilumab (ANTI-IL4RA) in Subjects with Eosinophilic Gastritis

This study is being conducted to determine the safety and effectiveness of a study drug called dupilumab in adolescents and adults with eosinophilic gastritis (EoG) with or without esophageal and/or duodenal eosinophilia.